|
Questions
|
Answer
|
|
During odontoblast differentiation,
where does fibronectin and decorin accumulate? |
Along the distal
pole of the differentiating cell |
|
At what place does
Dentin phospoprotein bond to collagen? |
In a highly
specific manner, DPP bonds to the e-band of the gap region of the type I collagen fibril |
|
Role of Dentin
Phospoprotein in mineralization |
1. Transport of
ions in to mineralization front; 2. Aggregation of collagen fibril; 3. Location of nucleation to specific region of collagen fibril; 4. Stabilization and orientation of formed collagen |
|
Presence of matrix
vesicle is limited to |
mantle dentin is
relatively less mineralized; collagen fiber are perpendicular to enamel; branched dentinal tubule; presence of mineralization by matrix mineralization |
|
Chains in Type III
collagen |
only alpha 1 chains
|
|
The only
glycosaminoglycans that is found unbound to any protein is |
Hyaluronic acid
|
|
composition of
glycosaminoglycans in mature pulp |
60% Hyaluronic
acid; 20% dermatan sulphate; 12% chondroitin sulphate and rest heparin sulphate |
|
composition of
glycosaminoglycans in developing pulp |
Chondroitin
sulphate is major amd hyaluronic acid minor component |
|
function of
versican |
contribute to the
bulk of proteoglycans and form large hydrated aggregates creating a gel |
|
function of decorin
|
binds to type I
collagen and helps in mineralization front |
Prof. Rooban Thavarajah
Oral and Maxillofacial Pathologist
List